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Bilateral ovarian involvement: A rare presentation of disseminated multiple myeloma
Author(s) -
Kazeminezhad Behrang,
Zaremirzaie Ali,
Mirafsharieh Abbas,
Soleimantabar Hussein,
Zahedifard Sara
Publication year - 2013
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.2012.01972.x
Subject(s) - medicine , multiple myeloma , plasma cell myeloma , pathology , ovary , bone marrow , immunoglobulin light chain , plasma cell , ovarian cancer , skull , surgery , cancer , antibody , immunology
Extramedullary spread of multiple myeloma is extremely rare. This paper reports a case of bilateral ovarian involvement in plasma cell myeloma. The patient was a 48‐year‐old Persian woman who experienced constitutional symptoms, bone pain and flashing for one year. Her condition showed multiple myeloma with lytic lesions of the skull, plasma cell infiltration in bone marrow and positive light chain lambda type in serum. Workup showed huge bilateral ovarian masses, and ovarian metastasis from plasma cell myeloma was confirmed after pathologic assessment. Multiple myeloma spread to ovary is rare and according to our knowledge, this is the fourth reported case of bilateral ovarian involvement in extramedullary multiple myeloma.