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Maternal carbon dioxide level during labor and its possible effect on fetal cerebral oxygenation: Mini review
Author(s) -
Tomimatsu Takuji,
Kakigano Aiko,
Mimura Kazuya,
Kanayama Tomoko,
Koyama Shinsuke,
Fujita Satoko,
Taniguchi Yukiko,
Kanagawa Takeshi,
Kimura Tadashi
Publication year - 2013
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.2012.01944.x
Subject(s) - hypocapnia , hyperventilation , medicine , carbon dioxide , oxygenation , fetus , cerebral blood flow , anesthesia , oxygen–haemoglobin dissociation curve , pregnancy , hypercapnia , acidosis , ecology , hemoglobin , genetics , biology
During pregnancy, and especially during labor, the maternal carbon dioxide level declines considerably. Maternal carbon dioxide levels show a close relation with fetal carbon dioxide levels. The latter affects fetal cerebral oxygenation by regulating cerebral blood flow and shifting the oxyhemoglobin dissociation curve. In addition, maternal hypocapnia appears to impair placental oxygen transfer. Thus, maternal hyperventilation may interfere with optimal fetal cerebral oxygenation. Here, we provide a brief overview of the literature relevant to this issue.