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Uterine cervical malignant granular cell tumor
Author(s) -
Guo Na,
Peng Zhilan,
Yang Kaixuan,
Lou Jiangyan
Publication year - 2012
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.2011.01788.x
Subject(s) - medicine , granular cell tumor , biopsy , metastasis , stroma , cervix , etoposide , lesion , chemotherapy , vaginal bleeding , radiology , uterine cervix , granular cell , pathology , surgery , cancer , immunohistochemistry , carcinoma , pregnancy , genetics , biology , central nervous system
Malignant granular cell tumor is relatively uncommon, constituting only 1–2% of all granular cell tumors. It is a rare and unusual tumor, especially in non‐typical sites, such as the uterine cervix, and grows more rapidly than benign granular cell tumor. It can be treated with surgical excision, but recurrence is possible and prognosis can be poor. A malignant granular cell tumor in the uterine cervix of a 37‐year‐old woman was incidentally diagnosed. The patient has a history of irregular vaginal bleeding. Uterine cervical biopsy under colposcope revealed a malignant granular cell tumor. After isophosphamide, etoposide, and cisplatin neoadjuvant chemotherapy, surgery was performed on the lesion, which approximately involved half the depth of cervical stroma. Computed tomography examination showed no local recurrence or distant metastasis during the 26‐month follow‐up period.