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Aromatase inhibitors in the treatment of recurrent ovarian granulosa cell tumors: Brief report and review of the literature
Author(s) -
AlHilli Mariam M.,
Long Harry J.,
Podratz Karl C.,
BakkumGamez Jamie N.
Publication year - 2012
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.2011.01698.x
Subject(s) - aromatase , medicine , granulosa cell , aromatase inhibitor , oncology , chemotherapy , stromal cell , radiation therapy , ovary , gynecology , cancer research , cancer , breast cancer
Granulosa cell tumors are ovarian sex cord stromal cancers that are unique for their indolent nature and late recurrence. Standard treatment regimens utilized include surgery, chemotherapy, and radiotherapy. However, hormonal suppression with aromatase inhibitors, which have shown promising results, may be a viable alternative to these modalities. We present a heavily pre‐treated, multi‐operated patient who experienced significant tumor shrinkage following treatment with an aromatase inhibitor for her recurrent granulosa cell tumor.