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Giant immature intracranial teratoma with antenatal cranial perforation
Author(s) -
Koizumi Koji,
Abe Emiko,
Kusanagi Yasuki,
Ito Masaharu
Publication year - 2010
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.2010.01311.x
Subject(s) - medicine , immature teratoma , teratoma , perforation , fetus , magnetic resonance imaging , prenatal diagnosis , gestational age , pregnancy , radiology , pathology , germ cell tumors , surgery , chemotherapy , materials science , genetics , biology , metallurgy , punching
Fetal brain tumors are very rare, and fetal survival is generally poor. Here we present a congenital intracranial immature teratoma, which was prenatally diagnosed. Prenatal ultrasonography and fetal magnetic resonance imaging detected the presence of a massive, heterogeneous intracranial tumor at 26 weeks gestational age. An intracranial tumor lacking normal intracranial structures was detected. The biparietal diameter was 13.1 cm, which is abnormally long. Fetal death occurred at 27 weeks of gestation due to cranial perforation. Postmortem histologic examination revealed the presence of an immature teratoma. Ultrasonography and magnetic resonance imaging are helpful in the prenatal diagnosis and evaluation of intracranial tumors. In conclusion, some cases of giant immature congenital teratoma develop antenatal cranial perforation.