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Case of polyhydramnios complicated by Opitz G/BBB syndrome
Author(s) -
Tajima Hiroko,
Itoh Hiroaki,
Mochizuki Ayako,
Nakamura Yuki,
Kobayashi Yukiko,
Hirai Kyuya,
Suzuki Kazunao,
Sugihara Kazuhiro,
Ohishi Akira,
Ohzeki Takehiko,
Kanayama Naohiro
Publication year - 2010
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.2010.01257.x
Subject(s) - hypertelorism , polyhydramnios , medicine , dysphagia , hypospadias , stalking , pediatrics , obstetrics , fetus , anatomy , pregnancy , surgery , psychiatry , biology , genetics
Opitz G/BBB syndrome is a congenital disorder characterized by midline defects, such as hypertelorism, cleft lip and/or palate, hypospadias, and by dysphagia often caused by laryngo‐tracheo‐esophageal abnormalities. We experienced a case of polyhydramnios in a male dichorionic diamniotic (DD) twin, who was diagnosed with Opitz G/BBB syndrome after birth. It is suggested that severe dysphagia was causatively associated with the development of polyhydramnios. In cases of Opitz G/BBB syndrome, boys are usually more heavily affected than girls, who generally manifest only hypertelorism. In the differential diagnosis of polyhydramnios of unidentified cause in male fetuses, it may be helpful to consider maternal facial characteristics, especially hypertelorism.