Premium
Carcinomatous meningitis from adenocarcinoma of the uterine cervix: A case report and literature review
Author(s) -
Yamauchi Noriyuki,
Sameshima Hiroshi,
Osato Kazuhiro,
Fukushima Kazuko,
Sato Yuichiro,
Ikenoue Tsuyomu
Publication year - 2010
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.2009.01163.x
Subject(s) - medicine , adenocarcinoma , complication , chemotherapy , cervix , metastasis , stage (stratigraphy) , cervical cancer , surgery , radical hysterectomy , cancer , paleontology , biology
Carcinomatous meningitis from uterine cervix‐related malignancies is a rare complication. We found only eight cases of meningeal metastasis from primary cervical carcinoma in the English‐language medical literature. However, its incidence has increased recently, probably because carcinomatous meningitis is being identified more often and survival time for the primary disease is extended. Thus, the clinical signs and methods for diagnosis are of great importance. A 47‐year‐old Japanese woman had a stage IIIb uterine cervical adenocarcinoma. She chose initial chemotherapy followed by radical hysterectomy and adjuvant chemotherapy. Ten months after initial chemotherapy and 6 weeks after the last chemotherapy, she suddenly presented with unexplained neurological signs. We performed a lumbar puncture, which demonstrated adenocarcinoma cells compatible with metastases from the primary cervical adenocarcinoma. She died 7 weeks later. This rare complication occurs in the advanced stage of cervical cancer. Lumbar punctures for neoplastic cells are advised, and the prognosis remains poor.