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Ovarian large cell neuroendocrine carcinoma
Author(s) -
Tsuji Takahiro,
Togami Shinichi,
Shintomo Nao,
Fukamachi Nobuyuki,
Douchi Tsutomu,
Taguchi Shuuhei
Publication year - 2008
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.2008.00916.x
Subject(s) - medicine , exploratory laparotomy , carboplatin , laparotomy , basal cell , ovary , epithelial ovarian carcinoma , stage (stratigraphy) , pelvic tumor , paclitaxel , ovarian carcinoma , neoplasm , pathology , oncology , radiology , ovarian cancer , surgery , chemotherapy , cancer , paleontology , biology , cisplatin
Ovarian large cell neuroendocrine carcinoma (LCNC) is a rare disease that is commonly associated with a surface epithelial and germ cell neoplasm component. A 46‐year‐old woman presented with a pelvic mass measuring 15 cm in diameter. She underwent an exploratory laparotomy with resection of the pelvic mass. Diffuse and nodular intra‐abdominal disseminations were observed. Stage III LCNC associated with squamous differentiation alone of the right ovary was diagnosed. The patient died of progressive disease 4 months postoperatively despite paclitaxel and carboplatin therapy. Ovarian LCNC associated with squamous differentiation component alone has never been reported, but its prognosis may be poor.