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Granulocyte‐colony stimulating factor for the treatment of ritodrine‐induced neutropenia
Author(s) -
Kikkawa Masashi,
Matsubara Shigeki,
Takatoku Masaaki,
Kuwata Tomoyuki,
Ohkuchi Akihide,
Izumi Akio,
Watanabe Takashi,
Suzuki Mitsuaki
Publication year - 2008
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.2008.00773.x
Subject(s) - ritodrine , medicine , neutropenia , granulocyte colony stimulating factor , adverse effect , granulocyte , anesthesia , pregnancy , chemotherapy , gestation , genetics , biology
We report on three pregnant women with ritodrine‐induced neutropenia who were successfully treated with granulocyte‐colony stimulating factor (G‐CSF). The neutropenia occurred after continuous intravenous infusion of ritodrine for preterm labor. Ritodrine was discontinued and G‐CSF was administered. Neutrophil counts returned to normal an average of 4.3 days after the administration. No infectious morbidity or adverse side‐effects occurred in the mothers or infants. G‐CSF is one possible treatment in women with ritodrine‐induced neutropenia.