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Fulminant type 1 diabetes during pregnancy: A case report and review of the literature
Author(s) -
Yamamoto Nari,
Fujita Yasuyuki,
Satoh Shoji,
Nakanami Naoyuki,
Sonoda Noriyuki,
Nakano Hitoo
Publication year - 2007
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.2007.00570.x
Subject(s) - medicine , fulminant , diabetic ketoacidosis , pregnancy , type 1 diabetes , ketoacidosis , diabetes mellitus , vomiting , pediatrics , type 2 diabetes , glycosuria , obstetrics , endocrinology , biology , genetics
Fulminant type 1 diabetes, classified as a subtype of nonautoimmune type 1 diabetes, may result in severe complications for both mother and fetus due to the sudden onset of diabetic ketoacidosis. Little is known about the clinical features of pregnancy with fulminant type 1 diabetes. We present a case of fulminant type 1 diabetes during pregnancy, along with a review of the published literature. A 31‐year‐old Japanese woman presented with sudden onset of nausea and vomiting at 36 weeks' gestation and was provisionally diagnosed with acute gastroenteritis. She was referred to us for investigation of exaggerated general fatigue and intrauterine fetal death. Based on blood and urinary examinations, she was diagnosed with diabetic ketoacidosis, caused by fulminant type 1 diabetes. Although her ketoacidosis was improved, insulin therapy was needed. Awareness of this disease can lead to prompt diagnosis and treatment and consequently, improved maternal and fetal prognosis.