Premium
Virilization in pregnancy due to a borderline mucinous ovarian tumor
Author(s) -
Pather Selvan,
Atkinson Kenneth,
Wang Iris,
Russell Peter,
Kesby Greg,
Carter Jonathan
Publication year - 2007
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.2007.00542.x
Subject(s) - virilization , medicine , ovary , gestation , stromal cell , pregnancy , ovarian tumor , androgen , gynecology , hormone , obstetrics , ovarian cancer , cancer , biology , genetics
Virilization in pregnancy due to borderline mucinous ovarian tumors is very rare. A case of a 28‐year‐old patient who was noted at 28 weeks' gestation to have marked virilization with raised serum androgens, ascites and a large complex right adnexal mass is presented. Delivery was carried out by cesarean section and at surgery a large tumor was noted in the right ovary. Histology revealed a borderline mucinous ovarian tumor with stromal luteinization, but there was no evidence of stromal invasion. Serum androgens returned to normal levels following surgery and the maternal virilization had resolved at the 6‐week postnatal visit. Stromal changes in borderline mucinous ovarian tumors may result in virilization due to androgen production; surgical removal is associated with an excellent clinical outcome.