Premium
Effects of ovarian drilling in middle Black Sea region Turkish women with polycystic ovary syndrome having normal and high body mass indices
Author(s) -
Demirturk Fazli,
Caliskan Ahmet C.,
Aytan Hakan,
Erkorkmaz Unal
Publication year - 2006
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.2006.00446.x
Subject(s) - medicine , polycystic ovary , follicular phase , menstrual cycle , body mass index , luteinizing hormone , testosterone (patch) , ovary , endocrinology , hormone , obesity , insulin resistance
Aim: To assess the effectiveness of laparoscopic ovarian drilling (LOD) in women with polycystic ovary syndrome (PCOS) with normal and high body mass indices (BMIs). Methods: We investigated the effects of LOD process on two different groups of Turkish women with normal ( n = 13) and high ( n = 12) body mass indices. Three‐puncture laparoscopy was performed under general anesthesia. Luteinizing hormone (LH), follicle‐stimulating hormone (FSH), dehydroepiandrosterone‐sulfate (DHEAS) and total testosterone (total T) levels were measured one menstrual cycle before the operation (in early follicular phase defined as day 3 of the menstrual cycle) and one menstrual cycle after the operation (in early follicular phase defined as day 3 of the menstrual cycle). Results: Ovarian drilling had a positive effect on FSH increase and DHEAS, total testosterone and LH/FSH ratio decrease; but BMI levels had no effect on these hormonal changes, respectively ( F = 0.343, P = 0564) ( F = 0.790, P = 0383) ( F = 0.083, P = 0776) and ( F = 0.816, P = 0376). Ovarian drilling had a positive effect on LH decrease and BMIs were effective on this change ( F = 6.946, P < 0.05). LH decrease in the group with normal BMI was significantly higher than the obese group with high BMI. Ten of 13 women with normal BMI (76.9%) and eight of 12 women with high BMI (66.6%) started to see regular menses 2 to 3 months after the procedure. Conclusion: Ovarian drilling is an effective procedure on PCOS. Women with lower BMI may benefit more from the procedure.