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Cervical Ureaplasma urealyticum colonization might be associated with increased incidence of preterm delivery in pregnant women without prophlogistic microorganisms on routine examination
Author(s) -
Mitsunari Masahiro,
Yoshida Souichi,
Deura Imari,
Horie Sayako,
Tsukihara Satoru,
Harada Tasuku,
Irie Takashi,
Terakawa Naoki
Publication year - 2005
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.2005.00246.x
Subject(s) - ureaplasma urealyticum , medicine , chorioamnionitis , preterm labor , obstetrics , colonization , incidence (geometry) , preterm delivery , cervix , gynecology , ureaplasma , pregnancy , gestation , microbiology and biotechnology , cancer , mycoplasma , biology , genetics , physics , optics
Aim: We examined whether the detection of Ureaplasma urealyticum DNA in the cervix is associated with preterm labor and delivery. Methods: Eighty‐two women (23 preterm labor cases and 59 controls) with no evidence of prophlogistic microorganisms on routine microbiologic examination were enrolled for this study. U. urealyticum colonization was examined using polymerase chain reaction of cervical swabs. Results: The positivity rate of U. urealyticum DNA in preterm labor cases was significantly higher than that in the controls (87.0% vs 45.8%, P = 0.0007). Women in the U. urealyticum ‐positive group more frequently delivered preterm compared with those in the negative group (36.2% vs 11.4%, P = 0.0111). In five cases that delivered preterm with histologically confirmed chorioamnionitis, U. urealyticum DNA was detected in the placenta. Conclusions: Cervical U. urealyticum colonization might be associated with preterm labor and delivery.