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Long‐term serological outcome of infants who received frozen–thawed milk from human T‐lymphotropic virus type‐I positive mothers
Author(s) -
Ando Yoshiya,
Ekuni Yutaka,
Matsumoto Yoshinari,
Nakano Shiro,
Saito Kensuke,
Kakimoto Kazuhiro,
Tanigawa Takuo,
Kawa Motohiro,
Toyama Takenori
Publication year - 2004
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.2004.00227.x
Subject(s) - infectivity , medicine , human t lymphotropic virus , serology , virus , antibody , full term , pregnancy , obstetrics , virology , immunology , biology , myelopathy , psychiatry , spinal cord , genetics
Aim: Human T‐lymphotropic virus type‐I (HTLV‐I) infection occurs via mothers’ milk during feeding. However, freeze–thaw processing can eliminate the infectivity of the mother's milk of HTLV‐I carriers. Methods: A long‐term follow‐up survey was conducted to investigate the HTLV‐I infectivity of frozen–thawed mothers’ milk among infants whose mothers were HTLV‐I seropositive. Results: Infants fed frozen–thawed mothers’ milk did not become HTLV‐I antibody‐positive up until 1 year old, and all children followed up until an age of 11–12 years were antibody negative. Conclusions: This study showed that freeze–thaw processing can eliminate the HTLV‐I infectivity of mothers’ milk, and that HTLV‐I carriers can indirectly feed their infants using frozen–thawed mothers’ milk as a way to prevent HTLV‐I infection.