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Prevalence of Human Papillomavirus Infection and Its Correlation with Cervical Lesions in Commercial‐Sex Workers in Japan
Author(s) -
Ishi Kazuhisa,
Suzuki Fujihiko,
Saito Akira,
Kubota Takeyoshi
Publication year - 2000
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.2000.tb01318.x
Subject(s) - medicine , human papillomavirus , cervical cancer , gynecology , obstetrics , hpv infection , dysplasia , cytology , cancer , pathology
Objective: To investigate the prevalence of the human papillomavirus (HPV) infection and its correlation with cervical lesions in commercial‐sex workers (CSWs) who attended a sexually transmitted disease (STD) clinic in an entertainment area in Tokyo. Methods: Surveys were conducted on 546 prostitutes and 233 control subjects. In all subjects, HPV detection was performed by the hybrid capture method. A cervical cytological examination was performed on 247 prostitutes and 233 control subjects. Results: The HPV‐positive rates in the two periods of study were higher (p < 0.01) in CSWs than in the control subjects. When the cytological grades were examined according to HPV‐positive rates, the proportion of cytologic Class IIIa to Class IV was significantly higher (p < 0.01) in the HPV‐positive CSWs than in the HPV‐negative CSWs or in the normal subjects. Conclusion: The high frequencies of HPV infection and cervical dysplasia in the CSWs in the present series might predict a higher risk of cervical cancer in this group of subjects.