Premium
Clinicopathological Study of Recurrent Uterine Cervical Squamous‐Cell Carcinoma
Author(s) -
Shiromizu Kenji,
Kasamatsu Takahiro,
Honma Tomokazu,
Matsumoto Koji,
Shirai Takako,
Takahashi Michiko
Publication year - 1999
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.1999.tb01183.x
Subject(s) - medicine , lymphatic system , lymph node , carcinoma , metastasis , lymph , cervical cancer , oncology , cancer , radiology , pathology
Objective: To improve prognoses of patients with recurrent uterine cervical squamous‐cell carcinoma. Patients and Methods: We clinicopathologically analyzed 464 patients with uterine cervical squamous‐cell carcinoma (126 positive, 338 negative pelvic lymph‐node metastasis) who were treated at the Saitama Cancer Center from January 1, 1976 to December 31, 1991. Results: The recurrence rates of negative pelvic lymph‐node metastasis patients were 14. 2% (39/274) in pT1b and 32.8% (21/64) in pT2b. But for positive lymph‐node metastasis patients the rates were 39.0% (23/59) in pT1b and 58.2% (39/67) in pT2b. The interval to recurrence was shorter in positve pelvic lymph‐node patients than in negative patients. The 5‐year survival rates after relapse of negative lymph‐node patients with intrapelvic, extrapelvic, and both‐sites recurrence were 53, 12, and 40%, respectively. But among distant recurrent sites, lung metastasis in negative lymph‐node patients and lymphatic tract metastasis brought relatively fair prognoses. Conclusions: Regular long‐term checks are necessary and active retreatments are recommended for patients with local recurrences, lung metastasis, or lymphatic vessel metastatic lesions.