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Effect of Daily Vaginal Disinfection on Duration of Gestation after Premature Rupture of the Membranes and on Infant Outcome
Author(s) -
Watanabe Takashi,
Minakami Hisanori,
Matsubara Shigeki,
Honma Yoko,
Uchida Akira,
Sato Ikuo
Publication year - 1998
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.1998.tb00091.x
Subject(s) - prom , medicine , gestation , obstetrics , gestational age , premature rupture of membranes , pregnancy , vaginal discharge , rupture of membranes , vaginal delivery , gynecology , pediatrics , genetics , biology
Objectives : We examined the effects of daily vaginal disinfection on the interval between premature rupture of the membranes (PROM) and delivery and on infant outcome. Methods : Daily vaginal disinfection with povidone iodine was performed on 43 women with PROM. The control group consisted of 59 women with PROM who did not undergo vaginal disinfection. In both groups, the infants born to these women were followed until 1 year of corrected age. Results : The degree of cervical dilatation, the leukocyte count, and the serum C‐reactive protein level on admission did not differ between the 2 groups. Although there was no difference in the gestational week at delivery between the groups, the interval between PROM and delivery was significantly longer in the disinfectant group than among the control subjects (9.5 ±14.9 days vs. 3.9 ±5.1 days, p < 0.01). There was no difference in infant outcome between the 2 groups. Conclusions : These findings suggest that daily vaginal disinfection with povidone iodine prolongs the duration of gestation in women with PROM and dose not have an adverse effect on the fetus.