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The Usefulness of Screaning for Chlamydial Trachomatis Infection with Cervical Mucus Leukocyte Esterase
Author(s) -
ElShourbagy Mahmoud,
Diab Khaled M.,
Abdalla Mahmoud Y.,
ElSalam Magda Abd,
Mohasb Shadia H.
Publication year - 1998
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.1998.tb00047.x
Subject(s) - leukocyte esterase , medicine , cervical mucus , chlamydia trachomatis , mucus , cervicitis , dipstick , gynecology , cervix , urine , biology , ecology , cancer
Objective : To evaluate the ability of leukocyte esterase dipstick test (LET) performed in cervical mucus to predict direct immunofluorescent (DIF)‐verified Chlamydia trachomatis (Ct) cervical infection. Method : Eighty women with inflammatory cervico‐vaginal smear were submitted to both an endocervical smear, to verify Ct cervicitis by DIF technique; and a cervical mucus sample to perform LET. Results of LET and DIF were matched. Results : Among 30 Chlamydial positive subjects, cervical mucus esterase test was positive in 28 (93.3%); while among 50 Chlamydial negative controls, esterase test was negative in 43 subject (86%). The sensitivity, specificity, positive and negative predictive values for LET were 93.3%, 86%, 80% and 95% respectively. Conclusion : Cervical mucus LET is a simple, cost effective screening test, with promising accuracy, for Ct cervical infection among women with inflammatory cervico‐vaginal smears.