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Hypersensitivity Reactions to Cisplatin following Multiple Uncomplicated Courses: A Report on Two Cases
Author(s) -
Onoyama Yoshimichi,
Umezu Takashi,
Kuriaki Yumiko,
Honda Naotoshi
Publication year - 1997
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.1997.tb00856.x
Subject(s) - medicine , cisplatin , hypersensitivity reaction , erythema , abdominal pain , ovarian cancer , anesthesia , surgery , chemotherapy , cancer
Two patients with ovarian cancer who had received multiple courses of cisplatin without complications experienced hypersensitivity reactions to cisplatin: one, involving intrahepatic artery infusion, manifested general erythema, dyspnea, and hypotension; the other, involving intravenous infusion, manifested abdominal pain, general erythema, and fever. When platinum‐containing agents are administered, patients should be closely monitored for hypersensitivity reactions, even in previously uncomplicated cases.