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The Behavior of Endometrial Hyperplasia: A Prospective Study
Author(s) -
Terakawa Naoki,
Kigawa Junzo,
Taketani Yuji,
Yoshikawa Hiroyuki,
Yajima Akira,
Noda Kiichiro,
Okada Hiroji,
Kato Junzo,
Yakushiji Michiaki,
Tanizawa Osamu,
Fujimoto Seiichiro,
Nozawa Shiro,
Takahashi Takeshi,
Hasumi Katsuhiko,
Furuhashi Nobuyuki,
Aono Toshihiro,
Sakamoto Atsuhiko,
Furusato Masakuni
Publication year - 1997
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.1997.tb00836.x
Subject(s) - medicine , prospective cohort study , endometrial hyperplasia , gynecology , hyperplasia
Abstract Objective : To clarify the behavior of endometrial hyperplasia in a prospective study. Method : Fifty‐one patients with endometrial hyperplasia were followed up for 6 months. Samples of endometrial tissues were taken by uterine endometrial biopsy every 4 weeks during the first 3 months and at the end of follow‐up. Results:/ In 69% (35/51) of the patients histological picture of the endometrium became normal during the observation period. The lesions persisted in 17% (6/35) of the patients with simple hyperplasia, in 25% (1/4) of those with complex hyperplasia, in 14% (1/7) of those with simple atypical hyperplasia, and in 80% (4/5) of the patients with complex atypical hyperplasia. In the remaining 3 patients with simple hyperplasia, the lesions progressed to complex atypical hyperplasia by the end of follow‐up, after showing a normal endometrium. Conclusion : Most cases of endometrial hyperplasia, except for complex atypical hyperplasia, disappeared spontaneously within a short period of time.