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Effect of Oocyte Retrieval from a Small Leading Follicle in Fixed‐Schedule in vitro Fertilization Program
Author(s) -
Nagai Seiichiro,
Yasumizu Takehiko,
Kasai Tsuyoshi,
Hirata Shuji,
Mizuno Kaoruko,
Kato Junzo
Publication year - 1997
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.1997.tb00826.x
Subject(s) - in vitro fertilisation , follicular phase , human fertilization , oocyte , medicine , follicle , human chorionic gonadotropin , andrology , gonadotropin , pregnancy rate , pregnancy , gynecology , hormone , embryo , biology , anatomy , genetics , microbiology and biotechnology
Objective : To evaluate the propriety of oocyte retrieval (OR) from a small leading follicle during a fixed‐schedule in vitro fertilization (IVF) program. Methods : OR was fixed only to take place on Wednesdays. Gonadotropin‐releasing hormone agonist treatment was initiated on the first day of the cycle, human menopausal gonadotrophin was given for 7 days starting on the next Monday, and human chorionic gonadotrophin (hCG) was given on the Tuesday before the OR. Patients were divided into 2 groups according to the follicular size observed before the day of hCG administration: Group 1 (141 cycles), with follicles > 16 mm in mean diameter; and Group 2 (38 cycles) with follicles of 10 to 16 mm in mean diameter. Results : Fertilization rates and the incidence of mature oocytes were higher in Group 1 than in Group 2. However, the mean number of oocytes recovered and pregnancy rates were similar in the 2 groups. Conclusion : It is worthwhile to retrieve the oocyte from a small leading follicle in a fixed‐schedule IVF program.