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Prevalence of Hemoglobin S and β‐Thalassemia in Northern Jordan *
Author(s) -
Sunna Elias I.,
Gharaibeh Nayef S.,
Knapp Dona D.,
Bashir Nabil A.
Publication year - 1996
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1111/j.1447-0756.1996.tb00929.x
Subject(s) - medicine , thalassemia , hemoglobin electrophoresis , incidence (geometry) , demographics , beta thalassemia , pediatrics , hemoglobin , environmental health , demography , physics , sociology , optics
Objective : The aim of this study was to determine the incidence of HbS and β‐thalassemia in the Northern Jordan. Study Design : The investigation targeted 3 areas of Northern Jordan. Blood samples from 2,290 volunteers were evaluated to determine the prevalence of HbS and β‐thalassemia by preparing a hemolysate for cellulose acetate electrophoresis. An additional 568 newborn samples were collected from the umbilical and analyzed for the presence of HbS using electrophoresis. Results : The overall prevalence of HbS and β‐thalassemia was 4.45% and 5.93%, respectively. The incidence of sickle cell trait in the newborn sample was 3.17%. The prevalence of both HbS and β‐thalassemia was higher in the Al‐Gor area in comparison to Ajloun and Irbid. Conclusion : A better understanding of the demographics of these diseases has the potential to aid in the more efficient utilization of health care resources and improved planning and provision of health care services.