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Anaphylactic Reaction to Cefazolin in Pregnancy
Author(s) -
Konno Ryo,
Nagase Satoru
Publication year - 1995
Publication title -
journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1340-9654
DOI - 10.1111/j.1447-0756.1995.tb00915.x
Subject(s) - cefazolin , anaphylactic reaction , pregnancy , anaphylaxis , medicine , obstetrics , anesthesia , immunology , microbiology and biotechnology , allergy , antibiotics , biology , genetics
Anaphylaxis is a rare event in pregnancy, but is one that can have serious implications for both the mother and fetus. We report a case of severe anaphylactic reaction to intravenous (IV) cefazolin (CEZ) given during labor with premature rupture of membranes. Maternal shock and prolonged fetal bradycardia occurred. Both the maternal and fetal outcomes were good following treatment with ephedrine, glucocorticoids, and emergency caesarean section.