Premium
A Study on the Hemostatic Effect of Sodium Alginate on Uterocervical Hemorrhage
Author(s) -
Nishiya Masashi,
Hareyama Hitoshi,
Makinoda Satoru,
Fujimoto Seiichiro
Publication year - 1994
Publication title -
asia‐oceania journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 0389-2328
DOI - 10.1111/j.1447-0756.1994.tb00451.x
Subject(s) - medicine , sodium alginate , hemostasis , hemostatic agent , surgery , sodium , anesthesia , chemistry , organic chemistry
We examined a sodium alginate preparation (Alto®) to determine its hemostatic effect, in comparison with other topical drugs, on hemorrhages in the uterocervical area. A total of 149 patients with hemorrhage from cervical erosion or after‐treatment bleeding of the cervix uteri were subjects in this trial, and 84 (79%) of 106 patients treated with this preparation experienced a hemostatic effect. A significant positive correlation (p<0.001) was noted between the degree of tissue adhesiveness and the hemostatic effect in all the drugs tested. As for the tissue adhesiveness, Alto was significantly more favorable (p<0.001) than both Thrombin and Francetin T powder. Because Alto was softened by tissue moisture, its topical adhesiveness could be increased, which suggested that Alto was superior in hemostatis.