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Cell‐Mediated Immunity in Cervical Intraepithelial Neoplasia
Author(s) -
Park Tchan K.,
Kim Soo N.,
Choi Dong H.,
Lee Chang H.
Publication year - 1992
Publication title -
asia‐oceania journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 0389-2328
DOI - 10.1111/j.1447-0756.1992.tb00318.x
Subject(s) - concanavalin a , cervical intraepithelial neoplasia , immune system , lymphocyte , cellular immunity , immunity , immunology , population , cell mediated immunity , cell , intraepithelial lymphocyte , interleukin 2 , medicine , biology , in vitro , cervical cancer , biochemistry , environmental health , cancer
Various immune parameters, i.e., peripheral T and B cell distribution, T cell sub‐population, interleukin 2 (IL‐2) activity and in vitro lymphocyte responses to phytohe‐magglutinin (PHA) and concanavalin A (Con A), were investigated in 24 pretreated patients with cervical intraepithelial neoplasia (CIN) and in 35 normal controls. Of the measured parameters, lymphocyte response to PHA was significantly lower in the CIN than control group (p<0.05). The values of all other measured parameters were similar in both groups.