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Efficacy of Cefoxitin for the Prevention of Postoperative Infection in Abdominal Hysterectomy
Author(s) -
Sutthijumroon S.,
Chandeying V.,
Tungphaisal S.
Publication year - 1990
Publication title -
asia‐oceania journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 0389-2328
DOI - 10.1111/j.1447-0756.1990.tb00359.x
Subject(s) - cefoxitin , medicine , abdominal hysterectomy , hysterectomy , antibiotics , surgery , prospective cohort study , statistical significance , postoperative fever , anesthesia , antibiotic prophylaxis , percutaneous , biology , bacteria , microbiology and biotechnology , genetics , staphylococcus aureus
Prophylactic effect of cefoxitin against postoperative infection at a dose of 2 g intravenous (single dose 30 minutes before the operation) was investigated using fever index in patients who underwent the elective, nonradical abdominal hysterectomy. The results obtained are summarized as follows. Total fever index values were 12.9±10.0 degree‐hours in the control group ( n =39), 11.3±9.7 degree‐hours in the study group ( n =39). There were no statistical significance between both groups. Data from this investigation does not suggest the concept that prophylactic antibiotics are beneficial in the reduction of postoperative infection. The results of this prospective study reflected in unnecessity of antibiotic prophylaxis in abdominal hysterectomy.