Premium
Epidermal Growth Factor‐Like Immunoreactivity in Human Endometrium
Author(s) -
Ishihara Satoko,
Taketani Yuji,
Mizuno Masahiko
Publication year - 1990
Publication title -
asia‐oceania journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 0389-2328
DOI - 10.1111/j.1447-0756.1990.tb00020.x
Subject(s) - paracrine signalling , autocrine signalling , endometrium , epidermal growth factor , endocrinology , medicine , receptor , menstrual cycle , growth factor , biology , epidermal growth factor receptor , chemistry , hormone
Epidermal growth factor (EGF)‐like immunoreactivity was detected in human endometrial tissues. The concentrations of the immunoreactivity fluctuated during the menstrual cycle. The highest levels were observed in the late proliferative phase with the concentrations being 0.50±0.06 ng/mg protein (M±SE, n =5). Considering the presence of EGF receptors in human endometrium, EGF‐like peptides may act in autocrine or paracrine fashions in human endometrium.