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Cryopreservation of Human Embryos as a Useful Tool for Infertile Couples
Author(s) -
Katayama K. Paul,
Stehlik Ed,
Roesler Mark,
Pentimalli Concetta,
Gunnarson Cindy,
Jagusch Susan,
Meyer Matthew
Publication year - 1990
Publication title -
asia‐oceania journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 0389-2328
DOI - 10.1111/j.1447-0756.1990.tb00008.x
Subject(s) - cryopreservation , embryo transfer , embryo cryopreservation , oocyte cryopreservation , embryo , in vitro fertilisation , andrology , pregnancy rate , gestation , pregnancy , gynecology , oocyte , human fertilization , medicine , obstetrics , biology , fertility preservation , fertility , anatomy , population , genetics , environmental health , microbiology and biotechnology
In order to improve the pregnancy rate per oocyte retrieval while reducing the chance of multiple‐gestations, a technique of cryopreservation of human embryos was used for our initial study consisting of 100 infertile patients undergoing in vitro fertilization (IVF) procedure. These patients combined a “fresh” embryo transfer with cryopreservation. The embryos were cryopreserved with 1,2‐propanediol. Twenty‐nine (29%) patients achieved ongoing pregnancies from the fresh embryo transfer. Thirty patients received a transfer of thawed embryos in a natural cycle. Nine of these patients achieved ongoing pregnancies. Combining these 2 transfers results in a 38% ongoing pregnancy rate. Forty‐one patients have yet to receive their frozen embryos. The current success rate in this study indicates that over 50% of the patients in this group can expect to become pregnant by the time all the cryopreserved embryos have been transferred.