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Uterine Malignancy Developing after Long Term Use of IUCD Additional Report of 2 Cases: Endometrial Stromal Sarcoma and Leiomyosarcoma
Author(s) -
Hsu ChienTien,
Hsu MeiLien,
Hsieh TungMing,
Lin ChungTsung,
Wang TaiTe,
Lin YunNan
Publication year - 1989
Publication title -
asia‐oceania journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 0389-2328
DOI - 10.1111/j.1447-0756.1989.tb00183.x
Subject(s) - endometrial stromal sarcoma , leiomyosarcoma , malignancy , medicine , sarcoma , pathological , endometrium , uterine sarcoma , gynecology , radiology , obstetrics , pathology
In our 2 previous papers published in this Journal, we had 5 cases of uterine malignancies developing after long term use of IUCD's. In the present paper 2 cases of such association are to be added. One case ATH with right adnexectomy was performed for persisting vaginal bleeding after 22 years of Lippes Loop application and recurrence 8 years after the first operation. Pathological diagnosis is endometrial stromal sarcoma. The other case is a leiomyosarcoma developing after 25 years of Lippes Loop application. Although no cause and effect relationship between IUCD use and uterine malignancy in human beings has been proved, the increase in such cases suggests to us that long term application should be avoided, particularly in view of the positive animal experiments. The successive detection of such cases in a relatively short period of time prompts us to make further studies to gain a deeper insight into such associations.