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Bleeding as a Consequence of Chorion Villus Sampling
Author(s) -
Liu David T. Y.,
Jeavons B.,
Preston C.,
Slater E.,
Symonds E. M.
Publication year - 1989
Publication title -
asia‐oceania journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 0389-2328
DOI - 10.1111/j.1447-0756.1989.tb00142.x
Subject(s) - medicine , obstetrics , spotting , pregnancy , abortion , incidence (geometry) , vaginal bleeding , gynecology , biology , genetics , physics , optics
A series of 4 separate studies were conducted to assess the incidence and short term consequence of bleeding associated with chorion villus sampling. Results support previous reports that risk of foetal‐maternal transfusion as suggested by a rise in maternal serum α‐fetoprotein (MSAFP) can occur. This occurrence is not consistent and need not be obvious even after therapeutic abortion. It is also transient and did not complicate mid‐trimester neural tube screening or subsequent course of pregnancy. Eighty‐seven percent of blood contaminating villus samples are of maternal origin. Following diagnosis 37% of patients reported some vaginal bleeding. This is mainly in the form of spotting which did not preclude normal pregnancy. Foetal loss occurred in 4 of the patients when bleeding considered heavier than spotting continued. In rhesus negative patients prophylactic anti‐D γ‐globulin is advised, since neither Kleihauer counts nor MSAFP estimation reliably detect all foetal‐maternal transfusions.