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Intrauterine Cytomegalovirus Infection Associated with Fetal Ascites and Oligohydramnios
Author(s) -
Kishikawa Tadao,
Kawarabayashi Tatsuhiko,
Hayasegawa Jun,
Sugimori Hajime,
Shimokama Tatsuro
Publication year - 1987
Publication title -
asia‐oceania journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 0389-2328
DOI - 10.1111/j.1447-0756.1987.tb00268.x
Subject(s) - oligohydramnios , fetus , ascites , medicine , cytomegalovirus , autopsy , pregnancy , obstetrics , pathology , physiology , biology , immunology , viral disease , virus , genetics , herpesviridae
Apparent fetal ascites and oligohydramnios were observed in a 21‐week pregnant woman. Careful ultrasonic examination did not reveal filling of the fetal bladder or kidneys. The pregnancy was terminated upon diagnosis of renal agenesis. Autopsy revealed the presence of kidneys, but typical intranuclear inclusion bodies were histologi‐cally observed in many fetal organs. It is speculated that an intrauterine cytomegalovirus infection caused multiple organ failures, including liver dysfunction and renal failure, resulting in fetal ascites and oligohydramnios, and that early occurrence of these anomalies indicates a severe infection and poor fetal prognosis.