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Non‐Immune Fetal Ascites: An Appraisal of Etiology and Outcome‐A Clinical and Pathological Review of 35 Cases
Author(s) -
Mir Nisar A.,
Perlman M. R.
Publication year - 1987
Publication title -
asia‐oceania journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 0389-2328
DOI - 10.1111/j.1447-0756.1987.tb00266.x
Subject(s) - medicine , polyhydramnios , ascites , etiology , asphyxia , necrotizing enterocolitis , hypoproteinemia , pathological , respiratory distress , meconium , oliguria , fetus , gastroenterology , obstetrics , pregnancy , surgery , renal function , genetics , biology
Thirty‐five cases of non‐immune fetal ascites, seen over a period of 11.5 years, are described. Associated maternal polyhydramnios was present in 9 and antenatal diagnosis was established or suspected in only 8 cases. Causes of ascites observed were: circulatory and cardiac (11), urinary (5), chylous (4), hepatobiliary (3), storage diseases (2), malignancy (2) and gastrointestinal disease (2). No cause for ascites was identified in 6 infants. The overall neonatal and infant mortality rate was 60%. Common indices of adverse prognosis include: prematurity, hydrops, severe respiratory distress, hypoproteinemia, pericardial or bilateral pleural effusions and severe birth asphyxia. Clinical problems encountered in the management of these infants are also reviewed.