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A Prospective Study of the Metabolic Effects of a Low Dose Combined Oral Contraceptive
Author(s) -
Liew Diana F.M.,
Ng Charles S.A.,
Yong Y.M.,
Ratnam S.S.
Publication year - 1986
Publication title -
asia‐oceania journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 0389-2328
DOI - 10.1111/j.1447-0756.1986.tb00158.x
Subject(s) - levonorgestrel , triglyceride , medicine , endocrinology , glucose tolerance test , ethinylestradiol , oral administration , carbohydrate metabolism , pregnancy , insulin , oral dose , cholesterol , population , insulin resistance , research methodology , family planning , biology , environmental health , genetics
The effects of a low dose combined oral contraceptive (OC) containing 30 μg ethinyl estradiol and 150 μg levonorgestrel, on carbohydrate and lipid metabolism were studied in 39 healthy women. An oral glucose tolerance test (OGGT) was performed before and 6 cycles after OC. Glucose tolerance and insulin response were impaired. There was no change in cholesterol levels. However, triglycerides were significantly lowered but this could be due to the “carry‐over” effects of pregnancy. Body weight was also significantly decreased but was not related to triglyceride change. There was no change in blood pressure after 6 cycles of OC.