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Changes in Plasma P, Ca, ALP, Calcitonin and Parathyroid Hormone with Age and after Oophorectomy in Women
Author(s) -
Kono Shinzo,
Lio Kazuo,
Takeuchi Kazuhiro,
Unoki Yasushi,
Go Shakugyo,
Mori Ichiro
Publication year - 1983
Publication title -
asia‐oceania journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 0389-2328
DOI - 10.1111/j.1447-0756.1983.tb00639.x
Subject(s) - medicine , endocrinology , calcitonin , oophorectomy , parathyroid hormone , myoma , bone resorption , hormone , menopause , resorption , calcium , uterus , hysterectomy , surgery
Plasma Ca, P, ALP, parathyroid hormone (cPTH) and calcitonin (CT) were determined in normal women and patients oophorectomized for uterine carcinoma and myoma (age 20–83). The plasma Ca, P and ALP levels increased markedly from age 50 and immediately after menopause, followed by a high plateau until advanced age. The plasma cPTH level tended to increase from the 30's to the 50's, followed by an increase until the 70's, while the plasma CT level tended to decrease with age. After oophorectomy, the incidence of increased plasma Ca, P and ALP was higher in the premenopausal group than in the postmenopausal group. These results indicate that the reduction of ovarian function with age is most closely related to resorption of bone mass, with which the changes of cPTH and CT might be associated.