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Management of Missed Abortion by Intramuscular Administration of 15(S) 15 Methyl Prostaglandin F 2 α
Author(s) -
Mapa Manik K.,
Singh Padamjit M.,
Misra Indra
Publication year - 1982
Publication title -
asia‐oceania journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 0389-2328
DOI - 10.1111/j.1447-0756.1982.tb00587.x
Subject(s) - abortion , prostaglandin , administration (probate law) , prostaglandin analogue , intramuscular injection , medicine , gynecology , prostaglandin f , anesthesia , political science , pregnancy , biology , law , genetics
Twenty two subjects with the diagnosis of missed abortion were induced with 15(S) 15 methyl Prostaglandin F 2 α by the intramuscular route of administration. The induction succeeded in all cases. The mean induction abortion interval was 16 hours with a range of 2 hours 30 minutes to 32 hours 10 minutes. The average dose of 15 methyl PGF 2 α required was 1675 μ g. Nine subjects (42%) had complete abortion. Seven subjects (31.8%) had no gastrointestinal side effects. The mean number of episodes of vomiting and diarrhoea was 1.3 and 0.8, respectively, 15(S) 15 methyl Prostaglandin F 2 α has high degree of efficacy in the management of missed abortion.