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Comparative study of different testings for estimating estriol —In relation to urinary and serum estriol levels—
Author(s) -
Sato Yoshiaki,
Torii Yuichi,
Takeuchi Shoshichi
Publication year - 1982
Publication title -
asia‐oceania journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 0389-2328
DOI - 10.1111/j.1447-0756.1982.tb00573.x
Subject(s) - estriol , urine , urinary system , correlation , chemistry , urology , medicine , chromatography , endocrinology , mathematics , estrogen , geometry
Summary We compared here the correlation between the colorimetric method and some other precise testing methods. The results are summarized as follows.1 A good correlation was observed between the colorimetric method and the LAIR (Neoest, New Estrotec) and HAIR (Estrotec) methods estimating E 3 in the urine. The calculated correlation coefficients between the E 3 kit and the Neoest, New Estrotec and Estrotec kits were 0.865, 0.729 and 0.788, respectively. Compared to the E 3 kit, the LAIR methods tended to give somewhat lower E 3 levels. 2 Among 15 samples with below 10 μ g/ml E 3 in the urine by the E 3 kit, 13 samples(86.7%) also showed coincident results by the LAIR method (Neoest). 3 A good correlation between serum E 3 level and urine E 3 level was observed at the low levels. Eight patients with a low serum E 3 level of below 10ng/ml revealed low urine E 3 levels of below 5 μ g/ml. Among 14 patients with low serum E 3 levels of below 20ng/ml, 12 showed E 3 levels in the urine of 5 μ g/ml, and the other 2 had urine levels below 10 μ g/ml. 4 It is concluded that the LAIR methods are useful in the mass screening of dysfunction of the feto‐placental unit in pregnancy in their rapidity and simplicity, although the E 3 levels so obtained tend to be somewhat lower than those obtained by the colorimetric method.