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Non‐shivering thermogenesis in brown adipose tissue and aging
Author(s) -
Yahata Takehiro
Publication year - 2004
Publication title -
geriatrics and gerontology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 57
eISSN - 1447-0594
pISSN - 1444-1586
DOI - 10.1111/j.1447-0594.2004.00168.x
Subject(s) - shivering , thermogenesis , brown adipose tissue , medicine , endocrinology , adipose tissue , thermogenin , glucagon , physiology , insulin
The aging‐induced decrease in non‐shivering thermogenic capacity was prevented in the genetically CCK‐A receptor deficient, diabetic obese OLETF rats, provably by an increase in the responsiveness of BAT to glucagon. The potential metabolic capacities can be sustained until aged period.