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Evaluation of novel sulfonylurea derivatives with a fused heterocyclic moiety as paddy herbicides that control sulfonylurea‐resistant weeds
Author(s) -
IKEDA HAJIME,
YAMATO SEIJI,
KAJIWARA YUKARI,
NISHIYAMA TAKAYUKI,
TABUCHI TAKANORI,
TANAKA YASUSHI
Publication year - 2011
Publication title -
weed biology and management
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.351
H-Index - 36
eISSN - 1445-6664
pISSN - 1444-6162
DOI - 10.1111/j.1445-6664.2011.00417.x
Subject(s) - sulfonylurea , moiety , pyridazine , acetolactate synthase , biology , sulfonyl , chemistry , stereochemistry , biochemistry , organic chemistry , enzyme , microbiology and biotechnology , insulin , alkyl
Herbicidal activity and acetolactate synthase (ALS) inhibition of sulfonylurea derivatives with a fused heterocyclic moiety bonded to a sulfonyl group were investigated. Some compounds that had an imidazo[1,2‐ b ]pyridazine moiety substituted at the 2‐position by chlorine or methyl controlled sulfonylurea‐resistant (SU‐R) weeds and showed inhibitory activity to ALS prepared from SU‐R Schoenoplectus juncoides shoot. There was a correlation between in vitro and whole‐plant herbicidal activity of the compounds mentioned above against SU‐R Schoenoplectus juncoides . Among them 1‐(2‐chloro‐6‐propylimidazo[1,2‐ b ]pyridazin‐3‐ylsulfonyl)‐3‐(4,6‐dimethoxypyrimidin‐2‐yl)urea, propyrisulfuron, was selected for further evaluation. Propyrisulfuron effectively controlled paddy weeds at doses of 70 and 140 g a.i. ha −1 with good rice selectivity in a field trial.