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Presentation and outcome of idiopathic thrombocytopenic purpura in a single Australian centre
Author(s) -
Choi P. YI.,
Gordon J. E. A.,
Harvey M.,
Chong B. H.
Publication year - 2012
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/j.1445-5994.2012.02740.x
Subject(s) - medicine , thrombocytopenic purpura , presentation (obstetrics) , immune thrombocytopenia , pediatrics , retrospective cohort study , surgery , immune system , immunology , platelet
Immune thrombocytopenia can be a therapeutic challenge with multiple first‐ and second‐line treatment options. A change in idiopathic thrombocytopenic purpura (ITP) definition and classification in recent consensus guidelines suggests that past descriptions of ITP presentation and outcome may be outdated. In this single centre retrospective analysis of patients with thrombocytopenia from 1 January 2005 to 1 June 2010, 139 patients met current ITP diagnostic criteria. About 54/139 were new presentations of primary ITP. Six‐ and 24‐month response rates were 39% and 30% respectively. About 26/54 patients did not require treatment at presentation: 15 were followed up for at least 6 months and none required treatment subsequently. These results suggest that almost half of all new primary ITP do not need treatment.