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Lymphoma, thymoma and the wooden man: stiff‐person syndrome post‐thymoma excision and non‐Hodgkin lymphoma remission
Author(s) -
Tsai T.,
McGrath R.
Publication year - 2012
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/j.1445-5994.2011.02688.x
Subject(s) - medicine , thymoma , lymphoma , etiology , stiff person syndrome , pathology , biochemistry , chemistry , glutamate decarboxylase , enzyme
Stiff‐person syndrome (SPS) is an uncommon yet under‐diagnosed, neuromuscular disorder characterised by progressive muscle rigidity with superimposed painful muscle spasms triggered by tactile, auditory or emotional stimulation. We describe the world's first case report of typical SPS in a patient with previously excised thymoma and treated non‐Hodgkin lymphoma. This is of relevance because of the increasingly elucidated autoimmune aetiology of SPS.