Premium
Rescue therapy with local intra‐arterial urokinase after poor clinical response with intravenous recombinant tissue plasminogen activator in acute ischaemic stroke
Author(s) -
Lee L. H.,
Chryssidis S.,
Jannes J.
Publication year - 2011
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/j.1445-5994.2011.02525.x
Subject(s) - medicine , thrombolysis , urokinase , recombinant tissue plasminogen activator , ischaemic stroke , stroke (engine) , acute stroke , tissue plasminogen activator , intensive care medicine , ischemic stroke , cardiology , ischemia , myocardial infarction , mechanical engineering , modified rankin scale , engineering
We report a case of combined intravenous and intra‐arterial thrombolysis in a patient presenting with acute ischaemic stroke. Progression to intra‐arterial thrombolysis in patients who fail to show clinical improvement within 6 h of symptom onset might be a safe treatment option at centres with access to stroke specialist and endovascular services. The purpose of this report is to demonstrate the efficacy and potential benefits of this rescue therapy.