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Fabry disease and Factor V Leiden: a potent vascular risk combination
Author(s) -
Tchan M.,
Sillence D.
Publication year - 2011
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/j.1445-5994.2011.02483.x
Subject(s) - medicine , warfarin , factor v leiden , aspirin , risk factor , cardiology , myocardial infarction , gastroenterology , thrombosis , venous thrombosis , atrial fibrillation
A 45‐year‐old man with heterozygous Factor V Leiden presented with his third cerebrovascular accident despite being on warfarin at a therapeutic international normalized ratio. Subsequent investigation revealed a second genetic diagnosis of Fabry disease. He then had an acute myocardial infarction whilst on aspirin and warfarin.