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Medically refractory neurosarcoidosis treated with infliximab
Author(s) -
Pereira J.,
Anderson N. E.,
McAuley D.,
Bergin P.,
Kilfoyle D.,
Fink J.
Publication year - 2011
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/j.1445-5994.2011.02457.x
Subject(s) - neurosarcoidosis , medicine , infliximab , refractory (planetary science) , sarcoidosis , surgery , tumor necrosis factor alpha , physics , astrobiology
Neurosarcoidosis can worsen despite standard immunosuppressive therapy, a situation for which there is no established medical management. We present three cases of medically refractory neurosarcoidosis treated with infliximab. All three patients showed a clinical response to this treatment and side effects were limited. A summary of reported cases of neurosarcoidosis treated with infliximab is included. This case series supports a role for infliximab in the treatment of patients with medically refractory neurosarcoidosis.