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Primary cytomegalovirus ileitis complicated by massive gastrointestinal haemorrhage in a patient with steroid refractory Crohn's disease
Author(s) -
Le S. T. T.,
Lee S. S. K.,
Prideaux L.,
Block A. A.,
Moore G. T. C.
Publication year - 2010
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/j.1445-5994.2010.02346.x
Subject(s) - medicine , ileitis , cytomegalovirus , refractory (planetary science) , disease , histopathology , crohn's disease , gastroenterology , cytomegalovirus infection , serology , immunology , pathology , herpesviridae , viral disease , human cytomegalovirus , virus , physics , antibody , astrobiology
A young man with known steroid refractory terminal ileal Crohn's disease developed torrential gastrointestinal bleeding necessitating an emergency ileal resection. Serology was indicative of primary cytomegalovirus (CMV) infection and this was confirmed with histopathology of the resected ileum. We highlight the difficulty in clinical practice of distinguishing between CMV infection and CMV disease as well as the different investigations available to aid in the diagnosis of pathogenic CMV disease.