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Guidelines for the prevention of sepsis in asplenic and hyposplenic patients
Author(s) -
Spelman D.,
Buttery J,
Daley A.,
Isaacs D.,
Jennens I.,
Kakakios A.,
Lawrence R.,
Roberts S.,
Torda A.,
Watson D. A. R.,
Woolley I.,
Anderson T.,
Street A.
Publication year - 2008
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/j.1445-5994.2007.01579.x
Subject(s) - medicine , sepsis , fulminant , intensive care medicine , asplenia , prophylactic treatment , antibiotic prophylaxis , antibiotics , immunology , surgery , spleen , microbiology and biotechnology , biology
Asplenic or hyposplenic patients are at risk of fulminant sepsis. This entity has a mortality of up to 50%. The spectrum of causative organisms is evolving as are recommended preventive strategies, which include education, prophylactic and standby antibiotics, preventive immunizations, optimal antimalarial advice when visiting endemic countries and early management of animal bites. However, there is evidence that adherence to these strategies is poor. Consensus‐updated guidelines have been developed to help Australian and New Zealand clinicians and patients in the prevention of sepsis in asplenic and hyposplenic patients.