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Urgent liver transplantation for acute liver failure due to parvovirus B19 infection complicated by primary Epstein–Barr virus and cytomegalovirus infections and aplastic anaemia
Author(s) -
So K.,
Macquillan G.,
Garas G.,
Delriviere L.,
Mitchell A.,
Speers D.,
Mews C.,
Augustson B.,
De Boer W. B.,
Baker D.,
Jeffrey G. P.
Publication year - 2007
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/j.1445-5994.2006.01293.x
Subject(s) - medicine , parvovirus , cytomegalovirus , complication , liver transplantation , aplastic anemia , virus , ganciclovir , transplantation , immunology , herpesviridae , virology , viral disease , bone marrow , human cytomegalovirus
An 11‐year‐old boy presented with hepatic failure secondary to parvovirus B19 infection, requiring urgent liver transplantation. His recovery was complicated by primary Epstein–Barr virus and cytomegalovirus infections. He subsequently developed aplastic anaemia that has been refractory to antithymocyte globulin and cyclosporine therapy and may now require bone marrow transplantation. We present this case to emphasize parvovirus as a rare cause of hepatic failure and of aplastic anaemia as a complication of the virus.