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Myeloid sarcoma of the uterus presenting as vaginal bleeding
Author(s) -
Pitz M. W.,
Maslyak O.,
Morales C.,
Seftel M. D.
Publication year - 2006
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/j.1445-5994.2006.01177.x
Subject(s) - medicine , asymptomatic , vaginal bleeding , myeloid , uterus , female circumcision , infiltration (hvac) , sarcoma , pathology , gynecology , pregnancy , physics , biology , genetics , thermodynamics
Extramedullary relapse of acute myeloid leukaemia may occur in sites such as the central nervous system, testes, and skin. Presentations in the female genital tract are uncommon and usually asymptomatic. In contrast, symptomatic uterine myeloid sarcoma is very rare. Treatment of this is generally unsuccessful, but is improved when systemic therapies are used. We study a case of a uterine relapse of acute myeloid leukaemia presenting as vaginal bleeding and successfully managed by local irradiation. The mechanism of preferential infiltration of uterine tissue requires further study.