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Sublingual nifedipine in human pregnancy
Author(s) -
Gallery E. D. M.,
Gyory A. Z.
Publication year - 1997
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1997.tb00961.x
Subject(s) - medicine , nifedipine , pregnancy , sublingual administration , medical emergency , obstetrics , anesthesia , calcium , genetics , biology
Background: Nifedipine is widely used for acute lowering of blood pressure in obstetric hypertensive emergencies. It has not been approved for this indication or widely assessed. Aims: To examine retrospectively the efficacy of nifedipine over a 12 month period in a high risk obstetric service. Methods: Chart review of all patients admitted to hospital in the antenatal period with moderate to severe hypertension. Description of their management, usage of nifedipine, and pregnancy outcome. Results: Sublingual nifedipine resulted in significant lowering of blood pressure without hypotension. Pregnancy outcome was satisfactory in all patients. Conclusions: Sublingual nifedipine was effective, easy to administer, and without serious complications in this retrospective study.