Premium
Adult T‐cell leukaemia lymphoma in an Aborigine
Author(s) -
Kirkland M. A.,
Frasca J.,
Bastian I.
Publication year - 1991
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1991.tb01380.x
Subject(s) - medicine , lymphoma , transverse myelitis , tropical spastic paraparesis , serology , pathology , t cell leukemia , cd8 , myelitis , leukemia , immunology , virology , spinal cord , antibody , multiple sclerosis , myelopathy , psychiatry , antigen
A 44‐year‐old Aborigine with Adult T‐cell Leukaemia/Lymphoma (ATLL) due to HTLV‐I is reported. He presented with transverse myelitis of subacute onset, and subsequently developed frank T‐cell leukaemia complicated by splenomegaly and hypercalcaemia. Cell surface marker studies showed a phenotype of CD3 + CD4 + CD8‐CD25 +, and serological and molecular studies confirmed HTLV‐I infection. This is the first report of ATLL in an Australian Aborigine.