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Disseminated prostatic carcinoma presenting with acute interstitial nephritis and microangiopathic haemolytic anaemia
Author(s) -
McGregor A. R.,
Moore M. L.,
Bailey R. R.,
Robson R. A.,
Lynn K. L.
Publication year - 1990
Publication title -
australian and new zealand journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0004-8291
DOI - 10.1111/j.1445-5994.1990.tb01296.x
Subject(s) - medicine , microangiopathic hemolytic anemia , malignancy , prednisone , gastroenterology , interstitial nephritis , renal biopsy , biopsy , urology , kidney , platelet , thrombotic thrombocytopenic purpura
A 74‐year‐old man with metastatic prostatic carcinoma developed acute oliguric renal failure, a microangiopathic haemolytic anaemia and thrombocytopaenia. A renal biopsy showed an acute interstitial nephritis but no changes suggestive of the haemolytic uraemic syndrome. He recovered normal renal function after treatment with haemodialysis and prednisone 20 mg daily for five days. Previous assumptions about the renal lesion in patients with malignancy‐associated microangiopathic haemolytic anaemia may need review.